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November 1, 2017
This work was led by Frederick Banting, a Canadian surgeon with the support of John McLeod, a physiologist and expert in diabetes
Besides the obvious infection risk, reused needles can introduce contaminants from the previous injection site back into the vial
This is a tolerability strategy, not a mechanistic requirement melanogenesis occurs regardless of injection timing
One thing to be wary of is that C-ratings can be used as a bit of a marketing tool so since the concept is a little more obtuse - I'd recommend comparing within a brand but not so much between brands
This work was supported by grants from the Postgraduate Education Innovation program of Shanxi Province (2024SJ155, YW), the central government guiding local funds for scientific and technological development (YDZJSX20231A062, CX), scientific and technological achievements transformation guidance project of Shanxi Province (202204021301067, CX), the National Natural Science Foundation of China (82350710800, 82374470, JX), National Key R&D Program of China (2024YFA0919200, JX), Shenzhen Science and Technology Program (KCXFZ20240903094059020, JX), and Shenzhen Medical Research Fund (B2302005, JX)
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